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Importance of Stable Rnase R in RNA Sequencing Projects

Nov.25.2024

There are many biotechnologies out there, but perhaps the one that stands out the most, alongside genetic editing technologies, is RNA sequencing - a genomic method which enables biologists to observe how genes are actively expressed. However, for RNA-seq to work properly, it is important to be very meticulous with the accuracy of the data, and one such thing is applying for stable RNase R. Tinzyme can provide you with high quality reagents that can definitely be a great augmentation for your work that require stable RNase R – particularly for projects associated with RNA sequencing.

About RNase R

As the name suggests, a vital component of producing an RNA sequencing program is an enzyme that is known as ribonuclease called as RNase R. This enzyme is catabolic in nature and helps in degrading single stranded RNA molecules but then becomes an arm of dependency. This is because once you have single strand RNA molecules, it’s pretty much impossible to recreate the experiment if you were able to get a great deal of RNA sequences with varying RNase R activity.

Understanding the Use of Stable RNase R in RNA Sequencing Processes

Sample Degradation

During the sequencing process, stable RNase R is essential for RNA synthesis by deforming RNA fragments before they are reconstructed.

Comprehensive Datasets

Consistency of results also depends on the integration of stable enzyme sequencing results, which does not allow for heterogeneity of results between different sequencing runs.

Improved Sensitivity

Furthermore, the stable RNase R also improves the sensitivity of RNA tests in cases with low transcript concentration whereby they are able to make certain inferences regarding the observations of the RNA sequences.

Making Sure of Quality with Tinzyme

We provide Tinzyme RNase R considering its crucial importance and in pure and fully functional state. RNase R is offered by Tinzyme in Lyophilized form which is well suited for storage and flexibility of use which enables researchers to avoid the worries of using these reagents and getting inaccurate or low quality result.

Conclusion

The necessity of RNase R in any RNA sequencing works is beyond any doubt as it is very robust. In order to achieve good, reproducible, and sensitive RNA sequencing data, it is crucial to employ RNase R during the RT phase. The range of reagents provided by Tinzyme guarantees researchers about their work.

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