DNase I Recombinant GMP Grade

Product Description:

Our DNase I Recombinant GMP Grade is a high-purity enzyme produced through recombinant technology, adhering to Good Manufacturing Practice (GMP) standards. This enzyme is specifically designed for the degradation of double-stranded DNA and is suitable for use in applications that require strict quality control and consistency.

Key Features:

• Produced through recombinant technology for high purity
• Adheres to GMP standards for quality assurance
• Efficient degradation of double-stranded DNA
• Suitable for RNA isolation and purification protocols
• Free from animal-derived components, reducing the risk of contamination
• Ideal for use in sensitive applications and regulated environments

Applications:

• RNA isolation and purification to remove contaminating DNA
• Preparation of RNA samples for RT-PCR and other RNA-based assays
• Elimination of genomic DNA from plasmid preparations
• Quality control of RNA samples prior to sequencing or microarray analysis
• Use in diagnostic assays and clinical laboratories
• Research and development in regulated environments

Our DNase I Recombinant GMP Grade is a reliable choice for laboratories that demand the highest standards of quality and consistency in their molecular biology workflows. Its production under GMP guidelines ensures that the enzyme meets the stringent requirements of sensitive applications and regulated environments.

Description

This product is a GMP grade recombinant deoxyribonuclease I (DNase I), which can randomly decompose single or double stranded DNA to produce 5'- p-terminal oligonucleotides. DNase I can cut double stranded DNA at will under Mg2+; Under Mn2+ condition, DNase I can cut DNA double strand at the same site to form flat end or stick end with 1-2 nucleotides protruding.

This product is a large-scale expression of recombinant DNase I in E. coli, with a molecular weight of about 39kD, which conforms to GMP production and quality management specifications. All raw and auxiliary materials are traceable.

Specification

• Heavy metal: ≤ 10ppm
• No virus, mycoplasma and other common pathogens
• Internal toxicity control: ≤ 10 EU / mg
• Volume activity(containing cCMP / RNase A): ≥ 40 Ku / ml
• Host protein residue: ≤ 50 ppm
• No RNase activity, cleavage activity
• Host DNA residue: ≤ 100 pg / mg
• There was no nonspecific nuclease activity

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